Francesco Bartolozzi began his study of art in Florence, where he was a pupil of painting, then continued to Venice to study engraving, and finally moved on to London in 1764 where he would stay for almost forty years. In London he produced his most notable works, such as Clytie, after Annibale Caracci, and The Virgin and Child, after Carlo Dolci. His work is also included in Boydell’s Shakespeare Gallery. In 1768 he was elected a founding member of the Royal Academy.
His talent and fame as an engraver grew when he developed a new technique for colored engraving, and was able to reproduce Holbein’s famous colored portrait drawings for the Royal Collection in 1793.
In 1802, Bartolozzi left England and moved to Portugal to act as the director of the National Academy in Lisbon. He remained there until his death in 1815.